ICI 2022: Image Guided Renal Denervation – The Time Is Now

This presentation by Rami Tzafriri, CBSET’s Director of Research and Innovation reviewed: The scientific data underlying the procedural dependence of radiofrequency (RF) denervation therapies, including a strong dependence of thermal distribution on the locations of the treating electrodes relative to nerves, veins and lymph nodes. Computational modeling results comparing the thermal patterns achieved by RF […]

Press Release: Preclinical Study Provides Guidance for Optimizing Safety and Efficacy of Endovascular Hepatic Denervation Devices to Treat Diabetes

“Our study has documented, for the first time, the distributionof nerves and adjacent anatomies surrounding human hepatic arteries. This is the foundation for the development of catheter-based denervation technologies, providing invaluable guidance on the preferred treatment locations and depths in order to be effective,” said Dr. Rami Tzafriri, Director of Research & Innovation for CBSET […]

Press Release: The procedural and anatomical determinants of second-generation renal denervation therapy are explained by local tissue anatomy, suggesting a new paradigm for treatment optimization: CBSET data published in Hypertension

“The combination of quantitative preclinical experiments and computational models have expanded our understanding of the mechanisms that facilitate circumferential nerve ablation and clinical efficacy. These data help complete the puzzle for device innovators, and aid in the advancement of specific approaches to treat diseases involving sympathetic denervation and modulation,” said Peter M. Markham, President and […]

Endovascular Today: Study Suggests That Local Tissue Anatomy May Explain Variable Patient Responses to RDN Therapy

May 4, 2015—CBSET, a not-for-profit preclinical research institute, announced that its scientists have published data and analyses that provide critical insights into the predictability, variability, and treatment success of catheter-based renal denervation (RDN) therapy. These data suggest that new, optimal alternative devices compared to first-generation RDN systems may enhance or assure efficacy, stated CBSET. The […]

DAIC: CBSET Scientists Indicate Preclinical Research is Critical to the Future of Renal Denervation

March 27, 2014 — Scientists at CBSET, a not-for-profit preclinical research institute dedicated to biomedical research, education and advancement of medical technologies, are reminding thought leaders in renal denervation that there is a seminal experimental and computational template for the more rational, comprehensive preclinical evaluation and optimization of renal denervation devices that can be utilized […]

DAIC: CBSET Presents Preclinical Development Data on Renal Denervation Devices

October 28, 2013 — CBSET, a not-for-profit preclinical research institute dedicated to biomedical research, education and advancement of medical technologies, will present data from the podium at the Transcatheter Cardiovascular Therapeutics annual scientific meeting (TCT 2013) that provides a seminal experimental and computational template for a more rational, comprehensive preclinical evaluation and optimization of renal […]