Kolandaivelu K, Tzafriri AR. Lost in translational filters between peers. Summary: In a recent issue of EuroIntervention, two articles(1)(2) and an editorial(3) detailed the translational journey taken by Qvanteq’s ultra-hydrophilic stent platform. Bench-top studies and animal experiments in two species of swine as well as rabbits suggested that a reduction in restenosis and stent thrombosis might […]
Tag Archives: 2017
Tufts CTSI Translational Day 2017: Lessons learned from the front lines
Rami Tzafriri, PhD and Michael Naimark, MS. “Lessons Learned from the Front Lines.” Summary: The Directors of Research and Innovation and Business Development presented advice and lessons learned from CBSET Inc.’s experiences on how to differentiate a new technology and navigate through a successful path to the market, and how to find the correct testing paradigm […]
Press Release: CILcare, CBSET, and Draper partner to accelerate hearing loss treatment and care
CAMBRIDGE, Mass., Nov. 6, 2017 – CILcare Inc., a leading clinical research organization specializing in ear disorders, and CBSET Inc., a non-profit translational research institute specializing in the advancement of novel therapies, announced today the initiation of a collaboration with Draper, a not-for-profit technology development company focused on the design, development and deployment of advanced […]
TCT 2017: Stent based tissue drug and binding target protein distributions: durable versus deployable coatings
Rami Tzafriri, PhD. “Stent based tissue drug and binding target protein distributions: durable versus deployable coatings.” Summary: We developed immunofluorescence (IF) methods to track drug and target protein distribution in stented arteries, to aid the development and assessment of novel stent designs. Xience Pro (74 μg Everolimus/3.0×15 mm, durable coating) and MiStent (135 μg Sirolimus/3.0×15 mm, […]
Press Release: CBSET Chairman Elazer Edelman, MD, PhD, has received the “TCT 2017 Career Achievement Award”
LEXINGTON, Mass., November 1, 2017 — CBSET Inc., a non-profit translational research institute that specializes in the advancement of novel therapies, announced today that Internationally renowned cardiologist, Elazer Edelman, MD, PhD, has received the “TCT Career Achievement Award” at TCT 2017 in Denver, Colorado. TCT Directors, Martin B. Leon, MD, and Gregg W. Stone, MD, […]
World Pharma Today: Auditory Therapy, Ototoxicity, and GLP Compliance: Will the promising market for ear disorder treatments follow ophthalmology’s dramatic growth curve?
by Michael Naimark, Director of Business Development, CBSET, Inc. and Marie-Pierre Pasdelou, PharmD, founder and the Chief Development Officer, CILcare Hearing research and development aims to prevent hearing loss, halt its progression, or reverse deficits through a range of approaches. Unfortunately progress to date has been limited and the FDA has yet to recognize any […]
ASR and AALAS: Benecalorie Nutritional Supplement as a Component of Liquid Diet in Swine
Misty Williams-Fritze DVM, MS, DACLAM. “Academy of Surgical Research: Benecalorie Nutritional Supplement as a Component of Liquid Diet in Swine.” Summary: Swine are commonly utilized in research of the gastrointestinal tract (GIT), where unobstructed access to the upper or lower GIT is necessary for biomedical device evaluation. We regularly use a liquid diet developed by our facility, […]
Academy of Surgical Research: Novel, Minimally Invasive, Toxin Administration into the Pericardial Space for the Developlment of Heart Failure in Swine
Jay Budrewicz, Kenta Nakamura, Mikhail Maslov, Anna Spognardi, Misty Williams-Fritze, Brett Zani, John Keating, Peter Markham, Mark Lovich, Elazer Edelman. “Novel, Minimally Invasive, Toxin Administration into the Pericardial Space for the Developlment of Heart Failure in Swine.” Summary: Due to the growing population of adult cancer survivors, there is a dramatically increasing patient population developing heart […]
SIB 2017: Particulate embolization from catheter coatings
Rami Tzafriri, PhD. ‘Particulate embolization from catheter coatings.’ Summary: Medical catheters permit minimally invasive external access for monitoring, imaging, sampling, local delivery of therapeutic agents, and placement of devices like endovascular stents, aneurysm coils and transcatheter valves. Catheter coatings are employed extensively as enhancers of device lubriciousness/ steerability and as platforms for local drug delivery. […]
Circulation: Randomized Comparison of Ridaforolimus- and Zotarolimus-Eluting Coronary Stents in Patients With Coronary Artery Disease: Primary Results From the BIONICS Trial
Kandzari DE, Smits PC, Love MP, Ben-Yehuda O, Banai S, Robinson SD, Jonas M, Kornowski R, Bagur R, Iniguez A, Danenberg H, Feldman R, Jauhar R, Chandna H, Parikh M, Perlman GY, Balcells M, Markham P, Ozan MO, Genereux P, Edelman ER, Leon MB, Stone GW. Randomized Comparison of Ridaforolimus- and Zotarolimus-Eluting Coronary Stents in Patients […]