Kolandaivelu K, Bailey L, Buzzi S, Zucker A, Ziogas A, Milleret V, Ehrbar M, Khattab A, Stanley JRL, Wong GK, Zani B, Markham PM, Tzafriri AR, Bhatt DL, Edelman ER. ‘Ultra-Hydrophilic Stents Promote Early Healing and Minimize Late Tissue Response: A Potential Alternative to Second-Generation Drug Eluting Stents.’
Summary: Clinical trials and meta-analyses demonstrate the low restenosis and stent thrombosis risks of next generation drug eluting stents (DES). Co-evolution of device, delivery technique, and drug-related factors all contribute, yet relative advantages are difficult to surmise. On a background of optimized contemporary bare metal stents (BMS), we asked if locally eluted drugs are still as useful or if simple design changes might obviate need for drug, further enhancing performance, manufacturability, and cost.
Poster presented at: Cardiovascular Research Technologies (CRT); 2015 Feb 21-24; Washington, DC. CRT-704. J Am Coll Cardiol Intv.2015;8(2_S):S44-S45.