Helge Struthoff, Lucas Lauder, Mathias Hohl, Alexander Hermens, Abraham Rami Tzafriri, Elazer R Edelman, Michael Kunz, Michael Böhm, Thomas Tschernig, Felix Mahfoud. “Histological examination of renal nerve distribution, density, and function in humans” Background: Renal denervation is optimised when guided by knowledge of nerve distribution. Aims: We aimed to assess sympathetic nerve distribution along the […]
Category Archives: Publications
Journal of Immunology and Regenerative Medicine: Early tissue growth and cell fate determination following segmental esophageal repair using a tissue engineered esophageal implant composed of a polyurethane scaffold seeded with autologous adipose-derived mesenchymal stromal cells
Sumati Sundaram, Karissa L. Paquin, Tina Roffidal, Greg Booker, Sherif Soliman, Jeff Bouchard, Elisaveta Todorova, Brett G. Zani, Raffaele Melidone, Saverio La Francesca, and William Fodor. “Early tissue growth and cell fate determination following segmental esophageal repair using a tissue engineered esophageal implant composed of a polyurethane scaffold seeded with autologous adipose-derived mesenchymal stromal cells.” […]
Frontiers in Gastroenterology: Comparison of PuraStat self-assembling peptide hydrogel versus mineral-based Hemospray for endoscopic hemostasis of upper and lower gastrointestinal lesions in pigs
Lisa Spirio, Eun Seok Gil, Kate O’neill, Elton Aleksi, Jay Budrewicz, and Raffaele Melidone. “Comparison of PuraStat self-assembling peptide hydrogel versus mineral-based Hemospray for endoscopic hemostasis of upper and lower gastrointestinal lesions in pigs.” Objective: To compare a RADA16-based self-assembling peptide hydrogel versus an inorganic powder-based spray device for controlling postoperative bleeding in upper and […]
BJU International: Evaluation of fluid absorption during flexible ureteroscopy in an in vivo porcine model
Christina Kottooran, Jeffrey Twum-Ampofo, Jason Lee, Jennifer Saunders, Marle Franco, Jay Budrewicz, Brian H Eisner. “Evaluation of fluid absorption during flexible ureteroscopy in an in vivo porcine model.” Objective: The purpose of this study was to evaluate the relationship between renal pelvis pressure and fluid absorption during ureteroscopy in a live porcine model. Materials and […]
Scientific Reports: Morphometric analysis of the human common hepatic artery (CHA) reveals a rich and accessible target for sympathetic liver denervation
Abraham Rami Tzafriri PhD, Fernando Garcia-Polite PhD, John Keating DVM DACVP, Raffaele Melidone DVM DACVP, Jennifer Knutson BS, Peter Markham MS, Elazer R. Edelman MD PhD, Felix Mahfoud MD. “Morphometric analysis of the human common hepatic artery (CHA) reveals a rich and accessible target for sympathetic liver denervation.” FULL ARTICLE Summary: Treatment of type 2 […]
Annual International Conference of the IEEE Engineering in Medicine & Biology Society: An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation
Georgia S Karanasiou, Panagiota I Tsompou, Nikolaos Tachos, Gianna E Karanasiou, Antonis Sakellarios, Savvas Kyriakidis, Luca Antonini, Giancarlo Pennati, Lorenza Petrini, Frank Gijsen, Farhad Rikhtegar Nezami, Rami Tzafriri, Martin Fawdry, Dimitrios I Fotiadis. “An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation.” Abstract: The introduction of […]
Annals of Otology, Rhinology & Laryngology: Safety and Feasibility of a Novel Esophageal Balloon for Circumferential Cytologic Sampling
N Kohli, A Blitzer, A Jahn, YJ Cho, J Budrewicz, K Enos, M Strome. “Safety and Feasibility of a Novel Esophageal Balloon for Circumferential Cytologic Sampling.” Summary: A prior publication introduced the Strome-Blitzer balloon’s ability to obtain circumferential esophageal cytologic sampling. This GLP study was requisite for FDA approval to determine if equivalent cell capture […]
Clinical Research in Cardiology: Combined renal and common hepatic artery denervation as a novel approach to reduce cardiometabolic risk: technical approach, feasibility and safety in a pre-clinical model
Márcio Galindo Kiuchi, Kavitha Ganesan, John Keating, Revathy Carnagarin, Vance B Matthews, Lakshini Y Herat, Gerard Goh, Leon Adams, Markus P Schlaich. “Combined renal and common hepatic artery denervation as a novel approach to reduce cardiometabolic risk: technical approach, feasibility and safety in a pre-clinical model.” Abstract: Background: Cardiovascular and metabolic regulation is governed by […]
JB & JS: Activation of Bone Remodeling Compartments in BMP-2-Injected Knees Supports a Local Vascular Mechanism for Arthritis-Related Bone Changes
Seeherman, Howard J. PhD, VMD; Li, X. Jian MD; Wozney, John M. PhD. “Activation of Bone Remodeling Compartments in BMP-2-Injected Knees Supports a Local Vascular Mechanism for Arthritis-Related Bone Changes.” Summary: Synovial membrane-derived factors are implicated in arthritis-related bone changes. The route that synovial factors use to access subchondral bone and the mechanisms responsible for […]
Biomaterials: Balloon-based drug coating delivery to the artery wall is dictated by coating micro-morphology and angioplasty pressure gradients
Abraham R. Tzafriri, Benny Muraj, Fernando Garcia-Polite, Antonio G. Salazar-Martín, Peter Markham, Brett Zani, Anna Spognardi, Mazen Albaghdadi, Steve Alston, Elazer R. Edelman. “Balloon-based drug coating delivery to the artery wall is dictated by coating micro-morphology and angioplasty pressure gradients.” Summary: Paclitaxel coated balloon catheters (PCB) were developed as a polymer-free non-implantable alternative to drug […]