Rami Tzafriri, Lee-Jae Jack Guo, Benny Muraj, Peter Markham, Curtis Genstler, Joseph Czyscon, Christopher Piere, Christopher Knapp, Elazer R. Edelman. Ultrasound-enhanced clot thrombolysis in a porcine model of pulmonary embolism. Ultrasound-assisted catheter-directed thrombolysis enhances right ventricular recovery after acute PE, but optimization is limited by lack of good animal models. We developed a porcine model […]
ISID1564 – Analyzing the effect of radiofrequency catheter ablation on tissue using a novel 3D imaging pipeline. Radiofrequency catheter ablation uses programmed electrical stimulation to alter or destroy cells causing irregular parenchymal activity. Despite its history of clinical adoption across a range of therapeutic areas, the 3D volume of ablated tissue has yet to be […]
Hodges, D., Tzafriri, R. Swine, the Other Tox Species. Summary: Since 1937, the Food and Drug Administration (FDA) has required preclinical testing of new drugs and biologicals for pharmacologic activity and acute toxicity in animals prior to their use in clinical trials. The guidance established the use of two animal species, a rodent and a […]
A Novel 3D Imaging Pipeline for Analyzing Radiofrequency Catheter Ablation in Preclinical Animal Models. Authors: Gianna Ferron(1), Neil Patel(1), Anthony Knesis(1), Yookyung Jung(1), Stefan Linehan(1), Tim Ragan(1), Jay Budrewicz(2), David Parrillo(2), Rami Tzafriri(2) Affiliations: (1) TissueVision, Inc., Newton, MA; (2) CBSET, Inc., Lexington, MA Abstract: Radiofrequency catheter ablation uses programmed electrical stimulation to alter or […]
Join CBSET at the 2023 AALAS National Meeting in Salt Lake City, UT, October 22-26. CBSET’s Director of Veterinary Services, Misty Williams-Fritze, is one of the authors of a poster presenting The Chinchilla Consortium: A Chinchilla Clinical Case Report Gold Mine. Related CBSET Services: CBSET GLP Preclinical Services Localized/Targeted Drug Delivery Computational Modeling of Local […]
Join CBSET and our partner CILcare at the Safety Pharmacology Society 2023 Annual Meeting, September 18-21, in Brussels, Belgium. We will be exhibiting in booth #506. CBSET Study Director, Donald Hodges, will be presenting “Swine, the Other Tox Species (or Beyond Medical Device Testing)” as part of a partner session with Dr. Michael Stonerook (AmplifyBio) […]
Join CBSET at the RESI Conference, September 18-20, at the Boston Park Plaza, Boston, MA The Redefining Early Stage Investments (RESI) conference series connects start-ups and early-stage investors and strategic channel partners. RESI maximizes fundraising companies’ efforts to find partners who are a fit for their technology and stage of development. RESI is uniquely cross-border […]
On January 30, 2023, CBSET submitted the first periodic technical report detailing completion of the animal study.
Join CBSET at EuroPCR, May 16-19, at the Palais des Congrès de Paris, 2 Place Porte Maillot, Paris France. This 4-day dynamic and immersive educational course enables cardiovascular professionals of every stripe – from interventional cardiologists to cardiac surgeons, interventional radiologists, imaging physicians, nurses and allied professionals – to stay up to date with the […]
DECODE 1st Networking Meeting Current State of the Art in the Use of DCBs in Clinical Practice On January 16-18, 2023 the DECODE consortium held its first Networking Meeting, which included both research and business-oriented topics. The first day was mainly about the research field, including lectures regarding anatomy, atherosclerosis, drug eluting devices and various […]