Tzafriri AR; Zani B; Stanley JRL; Markham PM; Nikanorov A; Edelman ER. ‘Lesion preparation with an orbital atherectomy system enhances paclitaxel deposition in calcified peripheral arteries.’
Poster presented at: Transcatheter Cardiovascular Therapeutics (TCT); Oct 11-14; San Francisco, CA.
Summary: It has been hypothesized that efficacy of DCB can be improved through treatment of calcified plaque with orbital atherectomy. We evaluated the effects of orbital atherectomy system (OAS) treatment on paclitaxel distribution in cadaveric samples of human peripheral arteries with substantial calcified plaque burdens.