EuroIntervention: Lost in translational filters between peers

Kolandaivelu K, Tzafriri AR. Lost in translational filters between peers. Summary: In a recent issue of EuroIntervention, two articles(1)(2) and an editorial(3) detailed the translational journey taken by Qvanteq’s ultra-hydrophilic stent platform. Bench-top studies and animal experiments in two species of swine as well as rabbits suggested that a reduction in restenosis and stent thrombosis might […]

The International Journal of Cardiology Imaging: Vessel centerline reconstruction from non-isocentric and non-orthogonal paired monoplane angiographic images

Mie Kunio, Caroline C. O’Brien, Augusto C. Lopes Jr., Lynn Bailey, Pedro A. Lemos, Guillermo J. Tearney, Elazer R. Edelman. Vessel centerline reconstruction from non-isocentric and non-orthogonal paired monoplane angiographic images. Summary: Three-dimensional reconstruction of a vessel centerline from paired planar coronary angiographic images is critical to reconstruct the complex three-dimensional structure of the coronary artery lumen […]

Respirology: Pharmacokinetics and safety of paclitaxel delivery into porcine airway walls by a new endobronchial drug delivery catheter

Tsukada H, Entcheva-Dimitrov P, Ernst A, Rafeq S, Keating JH, Seward KP, Yarmus L. Pharmacokinetics and safety of paclitaxel delivery into porcine airway walls by a new endobronchial drug delivery catheter. Summary: Intratumoral administration of chemotherapeutic agents is a treatment modality that has proven efficacious in reducing the recurrence of tumours and increases specificity of treatment […]

Tufts CTSI Translational Day 2017: Lessons learned from the front lines

Rami Tzafriri, PhD and Michael Naimark, MS. “Lessons Learned from the Front Lines.” Summary: The Directors of Research and Innovation and Business Development presented advice and lessons learned from CBSET Inc.’s experiences on how to differentiate a new technology and navigate through a successful path to the market, and how to find the correct testing paradigm […]

Press Release: CILcare, CBSET, and Draper partner to accelerate hearing loss treatment and care

CAMBRIDGE, Mass., Nov. 6, 2017 – CILcare Inc., the world’s leading clinical research organization specializing in ear disorders, and CBSET Inc., a non-profit translational research institute specializing in the advancement of novel therapies, announced today the initiation of a collaboration with Draper, a not-for-profit technology development company focused on the design, development and deployment of […]

TCT 2017: Stent based tissue drug and binding target protein distributions: durable versus deployable coatings

Rami Tzafriri, PhD. “Stent based tissue drug and binding target protein distributions: durable versus deployable coatings.” Summary: We developed immunofluorescence (IF) methods to track drug and target protein distribution in stented arteries, to aid the development and assessment of novel stent designs. Xience Pro (74 μg Everolimus/3.0×15 mm, durable coating) and MiStent (135 μg Sirolimus/3.0×15 mm, […]

Press Release: CBSET Chairman Elazer Edelman, MD, PhD, has received the “TCT 2017 Career Achievement Award”

LEXINGTON, Mass., November 1, 2017  — CBSET Inc., a non-profit translational research institute that specializes in the advancement of novel therapies, announced today that Internationally renowned cardiologist, Elazer Edelman, MD, PhD, has received the “TCT Career Achievement Award” at TCT 2017 in Denver, Colorado. TCT Directors, Martin B. Leon, MD, and Gregg W. Stone, MD, […]

World Pharma Today: Auditory Therapy, Ototoxicity, and GLP Compliance: Will the promising market for ear disorder treatments follow ophthalmology’s dramatic growth curve?

by Michael Naimark, Director of Business Development, CBSET, Inc. and Marie-Pierre Pasdelou, PharmD, founder and the Chief Development Officer, CILcare Hearing research and development aims to prevent hearing loss, halt its progression, or reverse deficits through a range of approaches. Unfortunately progress to date has been limited and the FDA has yet to recognize any […]

ASR and AALAS: Benecalorie Nutritional Supplement as a Component of Liquid Diet in Swine

Misty Williams-Fritze DVM, MS, DACLAM. “Academy of Surgical Research: Benecalorie Nutritional Supplement as a Component of Liquid Diet in Swine.” Summary: Swine are commonly utilized in research of the gastrointestinal tract (GIT), where unobstructed access to the upper or lower GIT is necessary for biomedical device evaluation. We regularly use a liquid diet developed by our facility, […]

Academy of Surgical Research: Novel, Minimally Invasive, Toxin Administration into the Pericardial Space for the Developlment of Heart Failure in Swine

Jay Budrewicz, Kenta Nakamura, Mikhail Maslov, Anna Spognardi, Misty Williams-Fritze, Brett Zani, John Keating, Peter Markham, Mark Lovich, Elazer Edelman. “Novel, Minimally Invasive, Toxin Administration into the Pericardial Space for the Developlment of Heart Failure in Swine.” Summary: Due to the growing population of adult cancer survivors, there is a dramatically increasing patient population developing heart […]