John Keating, Brett Zani, James RL Stanley, Peter Markham. ‘Assessment of a Novel Rabbit Atheroma Model Utilizing Combined Dietary Modification, Balloon Injury and Administration of Pro-Calcific Agents.’ Poster presented at: American College of Veterinary Pathologists (ACVP), Dec 3-7, 2016, New Orleans, LA.
Rami Tzafriri. ‘New and Revisited Targets for Autonomic Modulation: the Pathophysiology Behind.’ Invited Presentation at: Innovations in Cardiovascular Interventions (ICI), Dec 4-6, 2016, Tel Aviv, Israel.
Rami Tzafriri; Peter Markham; Brett Zani; Steve Alston; Elazer Edelman. ‘Multiple drug coated balloon exposures increase arterial permeability and drug retention.’ Presented at: Innovations in Cardiovascular Interventions (ICI), Dec 4-6, 2016, Tel Aviv, Israel. Summary: It is thought that increased dose or number of drug-coated balloon (DCB) inflations increases drug delivery and tissue retention – this […]
Peter Markham, MS and Rami Tzafriri, PhD. ‘Pre-clinical studies of implantable medical devices: Lessons from the front lines..’ Summary: Surveying three example cases of pre-clinical studies of combination medical devices, the presentation attempts to illustrate 3 key lessons: First follower – Don’t just follow first generation testing paradigm. Speed and differentiation are most important New product […]
Rami Tzafriri; Brett Zani; Steve Alston; Elazer Edelman. ‘Multiple drug coated balloon exposures increase arterial permeability and drug retention.’ Poster presented at: Transcatheter Cardiovascular Therapeutics (TCT), Oct 25-Nov 2, 2016, Washington, DC. Summary: It is thought that increased dose or number of drug-coated balloon (DCB) inflations increases drug delivery and tissue retention – this however has […]
LEXINGTON, Mass., Oct 28, 2016 — CBSET Inc. announced today that it has appointed Dr. Rami Tzafriri as Director of Research and Innovation. Since 2009, Dr. Tzafriri has held the position of Principal Scientist at CBSET, where he developed quantitative computational and experimental methods for evaluating combination drug and energy delivery devices. He is best known […]
LEXINGTON, Mass., Oct 27, 2016 — CBSET, Inc. announced today that it has appointed Michael Naimark as Director of Business Development, effective immediately. Most recently, he was employed by the Neural Stem Cell Institute (NSCI) as project manager overseeing the development of a cell-based therapy for macular degeneration under a 4-year award from the New York Stem […]
S Ewen; C Ukena; T Luscher; M Bergmann; P Blankestijn; B Cremers; E Blessing; O Doerr; H Nef; M Schlaich; F Sharif; MVoskuil; T Zeller; AR Tzafriri; E Edelman; Ml Boehm; FMahfoud. Anatomical and procedural determinants of catheter-based renal denervation Summary: Catheter-based renal sympathetic denervation (RDN) can reduce blood pressure (BP) and sympathetic activity in certain […]
L Bailey, AS; M Gilvarry; M Holian; R Tzafriri, PhD, J Keating, DVM, DACVP, E Edelman, MD, PhD, FACC. ‘Preclinical Evaluation of Mechanical Thrombectomy Devices in a Swine Clot Model.’ Summary: Successful recanalization (TICI ≥2b) using mechanical thrombectomy (MT) with stent retriever devices is associated with good outcomes in the treatment of ischemic stroke. Preclinical TICI […]
“Understanding and computationally modeling the determinants of drug release kinetics and tissue distribution can help further drive innovation at reduced cost.” – Rami Tzafriri, PhD, Principal Scientist, CBSET “Endovascular Drug Delivery and Drug Elution Systems: First Principles” Abraham Rami Tzafriri, PhD Elazer Reuven Edelman, MD, PhD “…The first principles outlined…serve as a handbook for features […]