ICI 2015: Enhanced Circumferential Ablation using a Multi-electrode Bipolar/Unipolar Over-the -Wire Renal Denervation RF Catheter System with Closed Loop Sensing

Tzafriri AR; Bailey L; Keating JH; Garcia-Polite F; Markham PM; Prutchi D; Edelman ER. ‘Enhanced Circumferential Ablation using a Multi-electrode Bipolar/Unipolar Over-the -Wire Renal Denervation RF Catheter System with Closed Loop Sensing.’ Podium presentation at: Innovations in Cardiovascular Interventions (ICI); Dec 13-15; Tel Aviv, Israel.

Press Release: MANTA Vascular Closure Device Safely and Effectively Closes Large Bore Arterial Access Sites: CBSET to Present Preclinical Data at ICI 2015

“Vascular access complications are a significant source of morbidity, especially for interventions such as TAVR that require large bore cannulation,” said Haim Danenberg, M.D., CBSET’s chief scientific advisor. “CBSET’s study demonstrates that MANTA is a safe and reliable large-bore percutaneous closure device.” LEXINGTON, Mass., Dec. 10, 2015 — Scientists at CBSET, a not-for-profit preclinical research […]

Press Release: Data provides new insights into the optimal balance between drug-eluting stent coating material properties and drug elution kinetics

“Drug eluting stents remain a ripe field for continued innovation. Until now, the focus on sustainable drug elution has strictly limited the choice of DES coating materials. Our study results confirm a new paradigm for optimizing coating biocompatibility,” said Rami Tzafriri, PhD, Principal Scientist, CBSET. LEXINGTON, Mass., Oct. 28, 2015 — CBSET, a not-for-profit preclinical […]

TCT 2015: Enhanced Circumferential Ablation using a Multi-electrode Bipolar/Unipolar Over-the-Wire Renal Denervation RF Catheter System with Closed Loop Sensing

Tzafriri AR; Bailey L; Keating JH; Garcia-Polite F; Markham PM; Prutchi D; Edelman ER. ‘Enhanced Circumferential Ablation using a Multi-electrode Bipolar/Unipolar Over-the-Wire Renal Denervation RF Catheter System with Closed Loop Sensing.’ Summary: Posthoc analysis of SYMPLICITY HTN-3 has revealed a trend for greater blood pressure reductions with increasing number of ablations and highlighted the difficulty of […]

TCT 2015: Lesion preparation with an orbital atherectomy system enhances paclitaxel deposition in calcified peripheral arteries

Tzafriri AR; Zani B; Stanley JRL; Markham PM; Nikanorov A; Edelman ER. ‘Lesion preparation with an orbital atherectomy system enhances paclitaxel deposition in calcified peripheral arteries.’ Poster presented at: Transcatheter Cardiovascular Therapeutics (TCT); Oct 11-14; San Francisco, CA. Summary: It has been hypothesized that efficacy of DCB can be improved through treatment of calcified plaque with […]

TCT 2015: Titratable drug delivery from drug filled stents

Tzafriri AR; Markham PM; Goshgarian J; Schulz-Jander D; Tunev S; Melder RJ; Stone GW; Edelman ER.‘Titratable drug delivery from drug filled stents.’ Poster presented at: Transcatheter Cardiovascular Therapeutics (TCT); Oct 11-14; San Francisco, CA. Summary: Polymer-free controlled drug elution has proved challenging for surface-modified drug eluting stents. Drug-filled stents (DFS; Medtronic, Santa Rosa CA) however, are […]